Differential interactions of halophilic and non-halophilic proteases with nanoparticles

Abstract

ncrease in the industrial use of nanomaterials and nanoparticles (NPs) make their release into the environment inevitable. This may lead to environmental contamination and exposure of the biological/ microbial diversity. Nanoparticles have been reported to impregnate the cells and interact with cellular biomolecules especially proteins and DNA, leading to nanotoxicity in many cases. The present work targets to study nanoparticle-protein interactions in-vitro, especially to assess their effects on extracellularly secreted enzymes. The primary extracellular enzymes viz. hydrolases and proteases could be the first to come in contact with environmentally released nanoparticles.