Guillain-Barre syndrome (GBS) is an immune-mediated disorder characterized by acute polyneuropathy, ascending paralysis and post infectious polyneuritis. Two-thirds of patients present with a history of recent upper respiratory tract or gastrointestinal infection. The clinical history, neurologic examination and laboratory assessment allow for a straightforward diagnosis in the majority of cases. However, primary biliary cirrhosis (PBC) is known to cause clinically detectable muscular weakness. It is therefore critical to differentiate between PBC-associated muscular weakness and GBS-induced paralysis. Here, we report a patient with a longstanding history of PBC who developed progressive weakness and respiratory failure due to GBS, which clinically mimicked PBC myopathy. This is the first reported association between GBS and PBC.
CITATION STYLE
Munday, W. R., DiCapua, D., Vortmeyer, A., & Gomez, J. L. (2015). Guillain-Barre syndrome mimics primary biliary cirrhosis-related myopathy. Oxford Medical Case Reports, 2015(4), 272–275. https://doi.org/10.1093/omcr/omv033
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