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Global resource distribution: Allocation of actin building blocks by profilin

Developmental Cell
DOI: 10.1016/j.devcel.2014.12.022
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Abstract

How cells regulate the distribution of a limited pool of actin between two competing structures has long been a mystery. Complementary studies from Suarez etal. (2015) and Rotty etal. (2015) now show that profilin controls the partitioning of actin monomers between competing actin networks assembled by Arp2/3 complex and formins or Ena/VASP.

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Henty-Ridilla, J. L., & Goode, B. L. (2015). Global resource distribution: Allocation of actin building blocks by profilin. Developmental Cell. Cell Press. https://doi.org/10.1016/j.devcel.2014.12.022

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