PGI2 is a novel sgi1-relative multidrug-resistant genomic Island characterized in proteus mirabilis

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Abstract

A novel 61,578-bp genomic island named Proteus genomic island 2 (PGI2) was characterized in Proteus mirabilis of swine origin in China. The 23.85-kb backbone of PGI2 is related to those of Salmonella genomic island 1 and Acinetobacter genomic island 1. The multidrug resistance (MDR) region of PGI2 is a complex class 1 integron containing 14 different resistance genes. PGI2 was conjugally mobilized in trans to Escherichia coli in the presence of a conjugative IncC helper plasmid.

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Lei, C. W., Chen, Y. P., Kong, L. H., Zeng, J. X., Wang, Y. X., Zhang, A. Y., & Wang, H. N. (2018). PGI2 is a novel sgi1-relative multidrug-resistant genomic Island characterized in proteus mirabilis. In Antimicrobial Agents and Chemotherapy (Vol. 62). American Society for Microbiology. https://doi.org/10.1128/AAC.00019-18

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