Evaluation of Injectable Platelet Rich Fibrin (I-PRF) with Bone graft around Immediate Dental Implant in Esthetic Zone

Abstract

Purpose: I-PRF was found to be effective in wound healing and bone regeneration, thus the purpose of this study was carried out to evaluate clinically and radiographically Injectable Platelet Rich Fibrin (I-PRF) around the immediate dental implant in the esthetic zone with xenograft. Material and methods: A total of twelve patients with unrestorable tooth/teeth in the esthetic zone were involved in this study. They were randomly divided into two groups; Group I (test group; n = 6) patients that received immediate implant placement with the use of I-PRF and xenograft and Group II (control group; n = 6) patients that received immediate implant placement with xenograft only. Clinically, the pain was evaluated for each patient by using the visual analog scale. Assessment of healing progress was by modified gingival index (MGI)and modified plaque index (MPI)at 1st, 3rd, and 6th month after implant placement. Radiography, the assessment of osteointegration can be by bone density at 1stand 6th month after implant placement. Results: The change in both MPI and MGI, there was statistically a significant difference. The study group showed a higher Change than the control group. At 1,3, and 7 days, there was a statistically non-significant difference in mean VAS in the two groups P=0.18. Regarding Change in Bone Density, the study group showed a higher Change than the control group with a statistically significant difference(P=0.002). Conclusion: The use of I-PRF with immediate dental implant placement offers a safe, compatible, and effective method for the healing process around immediate dental implants.