Type 2C protein phosphatases in plants

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Abstract

Type 2C protein phosphatases (PP2Cs) form a structurally unique class of Mg2+-/Mn2+-dependent enzymes. PP2Cs are evolutionary conserved from prokaryotes to higher eukaryotes and play a prominent role in stress signalling. In this review, we focus on the evolution, function and regulation of the plant PP2Cs. Members of a subclass of plant PP2Cs counteract mitogen-activated protein kinase pathways, whereas members of other subfamilies function as co-receptors for the phytohormone abscisic acid. Recent structural analyses of abscisic acid receptors have elucidated the mode of ligand-dependent regulation and substrate targeting. © 2012 The Authors Journal compilation © 2012 FEBS.

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Fuchs, S., Grill, E., Meskiene, I., & Schweighofer, A. (2013, January). Type 2C protein phosphatases in plants. FEBS Journal. https://doi.org/10.1111/j.1742-4658.2012.08670.x

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