Review: Using Metal Oxide Nanoparticles as Catalyst in Benzimidazoles Synthesis

Abstract

Heterocyclic compounds, such as benzimidazole derivatives, are a type of heterocyclic chemicals. Benzimidazole consists of a 6-atom benzene ring fused to the five-atom imidazole ring, which is an important structural property of this compound. A powerful inhibitor of various enzymes was used to investigate several pharmacological residences. Heterocyclic compounds, including benzimidazoles, are interested in being very effective compounds and are used in the preparation of many medicines, including as antiviral, anticancer, antiparasitic, antimicrobial, antihistamine, analgesic and as effective treatments for diabetes. Because of their stability, bioavailability, and have large organic activity, benzimidazole derivatives have multiple activities. Using various azole moieties, modifications to a few organic polymers was achieved. This article will discuss some of the current methodologies of synthesizing benzimidazoles and their pharmacological properties, as well as a variety of derivatives.