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Three sequential fermentative batches were carried out with cell recycle in four simultaneously operating bioreactors maintained at pH 6.5, 30°C, and 100 rpm. P. acidipropionici ATCC 4875 was able to produce propionic and succinic acid from sorbitol. The concentration of propionic acid decreased slightly from 39.5 ± 5.2 g L−1 to 34.4 ± 1.9 g L−1, and that of succinic acid increased significantly from 6.1 ± 2.1 g L−1 to 14.8 ± 0.9 g L−1 through the sequential batches. In addition, a small amount of acetic acid was produced that decreased from 3.3 ± 0.4 g L−1 to 2.0 ± 0.3 g L−1 through the batches. The major yield for propionic acid was 0.613 g g−1 in the first batch and succinic acid it was 0.212 g g−1 in the third batch. The minor yield of acetic acid was 0.029 g g−1, in the second and third batches.
Duarte, J. C., Valença, G. P., Moran, P. J. S., & Rodrigues, J. A. R. (2015). Microbial production of Propionic and Succinic acid from Sorbitol using Propionibacterium acidipropionici. AMB Express, 5(1). https://doi.org/10.1186/s13568-015-0095-6