Contribution of brownian rotation and particle assembly polarisation to the particle response in magnetic particle spectrometry

Abstract

The spectrometry of super-paramagnetic iron-oxide nanoparticles is a central tool for characterising particles that are used in Magnetic Particle Imaging. In Magnetic Particle Imaging, nanoparticles are excited by a magnetic field and the particle response is measured. Until now, the influence of the trajectory sequence on the dynamic particle relaxation has not been scoped. With a multi-dimensional Magnetic Particle Spectrometer, analysing the behaviour of different trajectories on the particles becomes possible. In this paper, the contribution of Brownian rotation and assembly polarisation on the particle signal is being analysed.