Role of platelet rich plasma gel in the wound healing of black Bengal goat

  • Ferdousy R
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Abstract

The study was conducted to evaluate the efficiency of platelet rich plasma (PRP) gel in the healing of skin wound.This experiment was carried out to exploit the therapeutic effects of PRP gel on healing process. A total of 72 surgical wounds were madein 12 goatsbearing weight 15-20 kg with the age 1-3 years. Goats were divided into four groups with three animals in each group. Wounds of four groups were treated with homogenous PRP gel, heterogenousPRP gel, sulphonilamide powder and tincture benzoinCo. or benzoin seal (control). The wounds were 3 cm length and 0.5 cm depth sutured with cross mattress using nylon. Follow-up observation was recorded from day 1 to day 30 postoperatively. Some morphological characters such as swelling area of wound, elevation of sutured line from the skin surface, width of sutured area and contraction length between 7 to 15 days were recorded to determine the healing process of the wounds. Besides morphological study, histopathological studies were also performed on day 1, day 2, day 3, day 5 and day 15 to evaluate the healing process.Homogenous PRP gel showed admirable results in the healing of the wounds produced in goat. All wounds treated with homogenous PRP gel showed no inflammation with dry sutured area and complete healing with massive hair follicular growth within 15-21 days. On histopathological study, demonstrated epithelial tissues with a normal morphology. The dermis showed flabby connective tissue with organized interconnecting collagen fibers running parallel to each other and new hair follicular growth inhealed area within 15 days, when wounds were treated with homogenousPRP gel.This study could help to consider natural biomaterial product specially PRP gel homogenous for a good healing of skin wounds with minimum complications. Further studies are necessary for the molecular investigation of healing process and proper establishment of commercially available of PRP gel and easiest finding theway of it'sapplication.

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Ferdousy, R. N. (2013). Role of platelet rich plasma gel in the wound healing of black Bengal goat. IOSR Journal of Agriculture and Veterinary Science, 6(5), 14–21. https://doi.org/10.9790/2380-0651421

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