Severe periodontitis is associated with insulin resistance in non-abdominal obese adults

Abstract

Context:Wehypothesized that insulin resistance, even with normal body weight (body mass index or waist circumference), can aggravate periodontitis severity. Objective: We investigated the associations between diabetes, insulin resistance, and severe periodontitis. Design: Among 29 235 total participants, 5690 subjects aged ≤ 30 y who had periodontal disease with community periodontal index (CPI) of 3 or 4 were selected for this study. Participants: Data were derived from the 2008-2010 Korea National Health and Nutrition Examination Survey. Results: Patients diagnosed with type 2 diabetes were more likely to have severe periodontitis (CPI 4) compared with patients with normal glucose tolerance or impaired fasting glucose (P = .001). Subjects with severe periodontitis had significantly higher prevalence of abdominal obesity, serum triglycerides, and insulin resistance (P values of .012,