Complete remission of IgA nephropathy after bone marrow transplantation for acute myeloid leukaemia

Abstract

IgA nephropathy is the most common primary glomerulonephritis, but the pathogenesis of IgA nephropathy is still unclear. A 32-year-old woman was found to have IgA nephropathy and acute myeloid leukaemia. She was treated with allogenic bone marrow transplantation (BMT). After BMT, immunoflourescent staining of IgA and proteinuria disappeared. These findings suggest bone marrow cells are involved in the pathogenesis of IgA nephropathy. We herein report a case of complete remission of IgA nephropathy after BMT for acute myeloid leukaemia. © The Author [2008]. Published by Oxford University Press on behalf of ERA-EDTA. All rights reserved.