A mini review: Proteomic analysis, a post-genomic approach

Abstract

We present here the proteome tool and its current state. Genomics and transcriptomics are briefly described and their limitations are discussed. The various aspects of proteomic approach are then presented and discussed. Proteomics is defined as the expressed complement of a genome. Technical aspects such as two dimensional gel electrophoresis, mass spectrometry and searches in generalist and EST databases changed the protein identification process. Proteomics can be divided into a systematic approach, or cell map proteomic and a pragmatic approach, or study of changes in protein expression.