Abstract
The Illumina Infinium HumanMethylationEPIC BeadChip is the new platform for highthroughput DNA methylation analysis, effectively doubling the coverage compared to the older 450K array. Here we present a significantly updated and improved version of the Bioconductor package ChAMP, which can be used to analyze EPIC and 450k data. Many enhanced functionalities have been added, including correction for cell-type heterogeneity, network analysis and a series of interactive graphical user interfaces.
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CITATION STYLE
Tian, Y., Morris, T. J., Webster, A. P., Yang, Z., Beck, S., Feber, A., & Teschendorff, A. E. (2017). ChAMP: Updated methylation analysis pipeline for Illumina BeadChips. Bioinformatics, 33(24), 3982–3984. https://doi.org/10.1093/bioinformatics/btx513
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