Alzheimer Hastalığı ve Anti-Alzheimer Etkili Bileşiklerin Yapılarının Araştırılması

Abstract

Alzheimer’s disease, the most common form of dementia, is a complex disease characterized by memory loss and other cognitive problems. Understanding the pathophysiology of Alzheimer’s disease, which has an increasing prevalence, and investigating the structures of compounds that are effective in the treatment of this disease will help to develop new effective drug molecules. In this sense, it is of great importance to investigate the hypotheses that are effective on the disease, the structure of the active compounds, and their mechanisms of action. Recent studies have shown that focus on obtaining stronger compounds that can affect more than one of the hypotheses that are effective in the pathology of the disease. In this review study, the important hypotheses that play a role in the pathology of Alzheimer’s disease and the structures of drug active compounds with proven anti-Alzheimer activity over these hypotheses are revealed.