Chemical constituents from typhonium giganteum rhizome and their antioxidant, tyrosinase inhibitory activities

Abstract

Fourteen constituents were isolated from the rhizome of Typhonium giganteum, which included one new compound, bis(2-ethylbutyl) terephthalate (1), along with thirteen known compounds (2–14). The structures of these compounds were elucidated by physical data analyses such as 1D NMR, 2D NMR and HR-ESI-MS. All compounds were tested for their antioxidant and tyrosinase inhibitory activities. Compounds 2, 5 exhibited obvious DPPH radical scavenging activities, while compounds 2, 5, 8, and 14 showed significant tyrosinase inhibitory activities.