Abstract
In a random sample of children (aged 9-11 years; n = 5629), who were studied according to the ISAAC phase II protocol, heterozygosity of the α1 antitrypsin (α1-AT) Pi genotypes MS or MZ, or low α1-AT plasma levels, were not associated with an increased risk of developing asthma. Asthmatics with low levels of α 1-AT were particularly prone to develop airway hyperresponsiveness and reduced lung function.
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CITATION STYLE
APA
Von Ehrenstein, O. S., Maier, E. M., Weiland, S. K., Carr, D., Hirsch, T., Nicolai, T., … Von Mutius, E. (2004). α1 Antitrypsin and the prevalence and severity of asthma. Archives of Disease in Childhood, 89(3), 230–231. https://doi.org/10.1136/adc.2002.023614
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