Case of “premonitory depression” in patient with major depressive disorder followed by pancreatic cancer

Abstract

We present the case of a patient who was diagnosed with “premonitory depression.” It is well known that cancer patients have higher rates of depression than general population. This is particularly true for those who suffer from pancreatic cancer, and such patients have a high incidence of depression compared to those who suffer from other malignancies. According to some hypotheses depression disorder associated with pancreatic cancer may be related to immunological interference with the activity of serotonin.