Abstract
AMP-activated protein kinase (AMPK) is emerging as a central regulator of the myocardial stress response. AMPK exerts important metabolic and non-metabolic actions and lies at the intersection of potential novel approaches to the treatment of coronary artery disease and type 2 diabetes. This review focuses on emerging data regarding the regulation of AMPK, the metabolic actions of AMPK in the heart and highlights the possible role of AMPK in novel cardioprotective strategies. © 2005 Elsevier Ltd. All rights reserved.
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CITATION STYLE
Miller, E. J., Russell, R. R., Li, J., & Young, L. H. (2005). AMPK - A pivotal rheostat in the control of cardiac metabolism. Drug Discovery Today: Disease Mechanisms. https://doi.org/10.1016/j.ddmec.2005.05.008
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