Durability of Spike Immunoglobin G Antibodies to SARS-CoV-2 Among Health Care Workers With Prior Infection

Abstract

Herd immunity is needed to reduce deaths, prevent transmission, and minimize the emergence of SARS-CoV-2 variants. The durability of serum antibodies against the spike protein of this virus provides insights into immunologic memory following natural infection.1 Recent literature supports that the levels of spike antibodies induced by natural infection correlate with neutralization and protect against subsequent infection.2 We evaluated the durability of naturally acquired spike immunoglobin (Ig) G antibodies to SARS-CoV-2 among a cohort of health care workers.