Recent advances in the development of hydrogel dressings for the treatment of pressure ulcers/injuries

Abstract

Pressure ulcers, also known as pressure injuries, are common conditions that result from chronic bedrest. These ulcers significantly affect quality of life and substantially burden individuals and society with health costs. The prevention and treatment of pressure ulcers is a primary concern for health care professionals. Dressings play a crucial role in the treatment of pressure ulcers. Hydrogels are innovative safe materials that show great promise for clinical applications. Recent research has demonstrated the potential of hydrogel dressings to promote the healing of pressure ulcers and chronic wounds. This review aims to summarize the mechanisms and effects of hydrogel dressings and to discuss considerations for their use in patients with pressure injuries under different circumstances. Hydrogel dressings, especially loaded with unique cargo, may represent promising new options for the treatment of pressure ulcers. However, additional clinical studies are urgently needed to validate the efficacy and accessibility of hydrogels in clinical practice.