Assessment of antioxidant activity of pure graphene oxide (GO) and composite V2O5/GO using DPPH radical and H2O2 scavenging assays

Abstract

In this research, the Co precipitation method was utilized to synthesize a nanocomposite of vanadium oxide (V2O5) and graphene oxide (GO). Pure GO was synthesized by the modified hammers method. Using a 1:2 ratio of GO and V2O5 and heating in the oven at 70 °C leading to the formation of V2O5/GO nanocomposite. By grafting of GO on V2O5 surface, a high range of graphene oxidation in V2O5/GO allowed for better reduction with V2O5 metal-oxide. The scanning electron microscope (SEM) images and X-ray diffraction (XRD) spectra provide evidence of the distinct phase of graphene oxide formation. The antioxidant activity of V2O5/GO nanocomposite was conducted in two vitro assays, focusing on neutralization of 2, 2-diphenyl-1-picrylhydrazyl (DPPH) and H2O2 radicals. The uniqueness of the nanocomposite was evident from its concentration-dependent antioxidant activities. Interestingly, the V2O5/GO samples has showed 60% antioxidant performance in the H2O2 assays compared to its constituent.