The inflammatory effects of diet, nutritional status, and severity of chronic kidney disease at Bogor City Hospital

Abstract

Diet and nutritional status play an important role in chronic kidney disease (CKD). Pro-inflammatory foods are linked to a decline in kidney function, whereas the nutritional status of obesity is a risk factor for CKD. This study aimed to analyze the relationship between  (DII), nutritional status, and CKD severity. This cross-sectional study was conducted between April and May 2023 at Bogor City Hospital.  A total of 64 patients with CKD were selected using accidental sampling.  Consumption data were collected from the SQ-FFQ, nutritional status was assessed using Body Mass Index (BMI), and disease severity was assessed using creatinine and estimated glomerular filtration rate (eGFR) levels. Data were analyzed using ANOVA, Kruskal-Wallis, Pearson, and Spearman correlation tests. Results: All subjects had positive DII scores, their nutritional status was mostly in the normal range (59,4%), and almost all subjects had CKD stage 5 (95,3%). No relationships were found between the DII score and creatinine level (p= 0,986) and eGFR (p= 0,359). There was also no relationship between nutritional status and creatinine (p= 0,985 ) and eGFR (0,442). In conclusion, a positive DII score indicated that all subjects consumed more pro-inflammatory foods. Actions are needed to get CKD patients with CKD  who consume more anti-inflammatory foods.