Screening for antiradical efficiency of 21 semi-synthetic derivatives of quercetin in a DPPH assay

7Citations
Citations of this article
18Readers
Mendeley users who have this article in their library.

Abstract

The group of 21 novel semi-synthetic derivatives of quercetin was screened for the antiradical efficiency in a DPPH assay. The initial fast absorbance decrease of DPPH, corresponding to the transfer of the most labile H atoms, was followed by a much slower absorbance decline representing the residual antiradical activity of the antioxidant degradation products. Initial velocity of DPPH decolorization determined for the first 75-s interval was used as a marker of the antiradical activity. Application of the kinetic parameter allowed good discrimination between the polyphenolic compounds studied. The most efficient chloronaphthoquinone derivative (compound Ia) was characterized by antiradical activity higher than that of quercetin and comparable with that of trolox. Under the experimental conditions used, one molecule of Ia was found to quench 2.6±0.1 DPPH radicals. Copyright © 2013 SETOX & IEPT, SASc.

Cite

CITATION STYLE

APA

Milackova, I., Kovacikova, L., Veverka, M., Gallovic, J., & Stefek, M. (2013). Screening for antiradical efficiency of 21 semi-synthetic derivatives of quercetin in a DPPH assay. Interdisciplinary Toxicology, 6(1), 13–17. https://doi.org/10.2478/intox-2013-0003

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free