Functional activities of Philippine wild strain of Coprinus comatus (O. F. Müll. : Fr.) Pers and Pleurotus cystidiosus O. K. Miller grown on rice straw based substrate formulation

Abstract

In order to determine the nutraceutical and pharmacological potential of Philippine wild strain of Coprinus comatus and Pleurotus cystidiosus, the antibacterial property, phytochemical composition, and antioxidant activity were evaluated. Both ethanol and acetone basidiocarp extracts exhibited antibacterial activity against Staphylococcos aureus. Coprinus comatus ethanol extract produced wider zone of inhibition than acetone extract while Pleurotus cystidiosus acetone extract exhibited larger zone of inhibition than the ethanol extract. Moreover, the immobilized mycelia discs of both species did not exhibit antibacterial activity against Staphylococcos aureus and Escherichia coli. Phytochemical screening revealed the presence of alkaloids, flavonoids, saponins and terpenoids in both mushroom species. Steroids and cardiac glycosides were absent in Pleurotus cystidiosus while tannins were not detected in both species. Pleurotus cystidiosus registered higher DPPH