A Mild and Efficient Method for the Syntheses and Regioselective Ring-Opening of Aziridines

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Abstract

We have developed a new synthetic method for the synthesis of aziridines using Chloramine-T as an effective reagent in the presence of NH 2OH·HCl and NaIO 4. We found that the same combination of NH 2OH·HCl and NaIO 4is also very effective for nucleophilic ring opening of aziridines.

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Ghosal, N. C., Mahato, S., Chatterjee, R., Santra, S., Zyryanov, G. V., & Majee, A. (2017). A Mild and Efficient Method for the Syntheses and Regioselective Ring-Opening of Aziridines. SynOpen, 1(1), 15–23. https://doi.org/10.1055/s-0036-1588809

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