Automated detection of knee cystic lesions on magnetic resonance imaging using deep learning

Abstract

Background: Cystic lesions are frequently observed in knee joint diseases and are usually associated with joint pain, degenerative disorders, or acute injury. Magnetic resonance imaging-based, artificial intelligence-assisted cyst detection is an effective method to improve the whole knee joint analysis. However, few studies have investigated this method. This study is the first attempt at auto-detection of knee cysts based on deep learning methods. Methods: This retrospective study collected data from 282 subjects with knee cysts confirmed at our institution from January to October 2021. A Squeeze-and-Excitation (SE) inception attention-based You only look once version 5 (SE-YOLOv5) model was developed based on a self-attention mechanism for knee cyst-like lesion detection and differentiation from knee effusions, both characterized by high T2-weighted signals in magnetic resonance imaging (MRI) scans. Model performance was evaluated via metrics including accuracy, precision, recall, mean average precision (mAP), F1 score, and frames per second (fps). Results: The deep learning model could accurately identify knee MRI scans and auto-detect both obvious cyst lesions and small ones with inconspicuous contrasts. The SE-YOLO V5 model constructed in this study yielded superior performance (F1 = 0.879, precision = 0.887, recall = 0.872, all class mAP0.5 = 0.944, effusion mAP = 0.945, cyst mAP = 0.942) and improved detection speed compared to a traditional YOLO model. Conclusion: This proof-of-concept study examined whether deep learning models could detect knee cysts and distinguish them from knee effusions. The results demonstrated that the classical Yolo V5 and proposed SE-Yolo V5 models could accurately identify cysts.