Abstract
The novel 3H-spiro[1-benzofuran-2-cyclopentan]-3-one skeleton has been made accessible by different routes. One- and two-step protocols lead to tricyclic and tetracyclic benzofuranones 2 and 3, respectively. A four-step synthesis to spirocompound 4 is described. The novel spirocyclic benzofuranones display modest to no inhibition of the human peptidyl prolyl cis/trans isomerase Pin1. © 2008 by MDPI.
Author supplied keywords
Cite
CITATION STYLE
Braun, M., Hessamian-Alinejad, A., De Lacroix, B. F., Alvarez, B. H., & Fischer, G. (2008). Novel spiroannulated 3-benzofuranones. Synthesis and inhibition of the human peptidyl prolyl cis/trans isomerase Pin1. Molecules, 13(4), 995–1003. https://doi.org/10.3390/molecules13040995
Register to see more suggestions
Mendeley helps you to discover research relevant for your work.
