Antifungal Resistance of Candida Species in Bacolod City, Philippines

Abstract

Candida species, a group of opportunistic infection-causing microorganisms, has shown an increasing pattern of resistance against certain antifungal drugs through time. Thus, this retrospective study was conducted to describe the antifungal resistance of Candida species isolated from a tertiary hospital in Bacolod City, Philippines from July 2017 to July 2018. A total of 184 Candida species were isolated from clinical specimens with C. albicans (61%) having the highest frequency followed by C. tropicalis (15%). Most of these Candida species were isolated from older adults (78.26%) and mid adults (15.76%). Additionally, Candida species were frequently present in respiratory specimens (69.02%) and urine specimens (20.65%). Moreover, resistance among the fungal isolates was noted against fluconazole and voriconazole with least resistance to micafungin and caspofungin.