Treatment of Scedosporium apiospermum brain abscesses with posaconazole

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Abstract

A 41-year-old man with acute lymphoblastic leukemia developed multiple Scedosporiurn apiospermum brain abscesses. The infection progressed despite neurosurgical drainage and treatment with itraconazole, amphotericin B, and ketoconazole, but the brain abscesses completely resolved after treatment with posaconazole alone.

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Mellinghoff, I. K., Winston, D. J., Mukwaya, G., & Schiller, G. J. (2002). Treatment of Scedosporium apiospermum brain abscesses with posaconazole. Clinical Infectious Diseases, 34(12), 1648–1650. https://doi.org/10.1086/340522

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