Cardiac findings in children with juvenile Dermatomyositis at disease presentation

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Abstract

Background: Juvenile Dermatomyositis (JDM) is a pediatric vasculopathy characterized primarily by skin and muscle involvement. Cardiac findings have been reported in children with JDM but have rarely been investigated in detail. Methods: We aimed to describe the relevant clinical and laboratory cardiac findings of a cohort of patients with JDM, followed at one centre, at disease diagnosis. Results: We performed a retrospective review of 105 patients with JDM, followed from 1991 to 2007. Six of 70 patients (9%, 6% of the entire cohort) had abnormal electrocardiographic (ECG) findings, while 26 of 54 patients (48%, 25% of the entire cohort) had abnormal echocardiographic (echo) findings. Many of these findings were either mild or unlikely to be a result of JDM. Conclusions: Our findings suggest that cardiac abnormalities at JDM disease onset are frequently seen, but are rarely significant findings due to disease; however, JDM patients should be considered for screening for cardiac disease as late cardiac complications are well recognized.

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Cantez, S., Gross, G. J., MacLusky, I., & Feldman, B. M. (2017). Cardiac findings in children with juvenile Dermatomyositis at disease presentation. Pediatric Rheumatology, 15(1). https://doi.org/10.1186/s12969-017-0182-0

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