P2O5/SiO2 as a new, efficient and reusable catalyst for preparation of 4,4'-epoxydicoumarins under solvent-free conditions

Abstract

An efficient solvent-free procedure for the preparation of 4,4'-epoxydicoumarins via the ondensation of 4-hydroxycoumarin with aldehydes in the presence of catalytic amount of phosphorus pentoxide/silica gel at 110 °C is described. The advantages of this method are generality, high yields, short reaction times, ease of product isolation, low cost and ecologically friendly. © Copyright E-Journal of Chemistry 2004-2011.