Assessment of Biochemical and Hematological Parameters in the CRF of Before and After Hemodialysis at Martyr Mohammed El-Najjar Hospital in Gaza Strip, Palestine

Abstract

There are limited data on the assessment biochemical and hematological profile in the CRF (CRF) of before and after hemodialysis in the Gaza Strip. The study aimed to evaluating some biochemical parameters and hematological profile in the CRF of before and after hemodialysis at Martyr Mohammed El-Najjar Hospital in Rafah, Gaza Strip, Palestine. Forty-three (end-stage renal disease) ESRD patients, aged 20-70 years old who were referred to Martyr Mohammed Youssef Al-Najjar Hospital in Rafah for the hemodialysis department. 43 apparently healthy individuals matched for ages were used as a control group for comparisons. The results showed that after-dialysis higher statistically significant in Hb, RBC, HCT, PLT, AST, ALT, ALP and Ca level than before-dialysis. While Ph, WBC, RDW, creatinine (Cr.), Urea was lower statistically significant in after hemodialysis than before-dialysis (P < 0.05). theses indicate to: chronic kidney disease shows abnormal hematological parameters, precisely reduced levels of RBC count, hemoglobin, hematocrit, and platelet count, in addition, before-dialysis patients are more anemic and thrombocytopenic than after-dialysis patients and this is may indicate of lack of blood pressure and type2 diabetes mellites (T2DM) control in these patients. AST& ALT activities vary in concentration before and after hemodialysis and make the after-dialysis patients are higher than before-dialysis.