Glass fibre paper-based test strips for sensitive SERS sensing

Abstract

We present paper-based test strips for chemical sensing with surface enhanced Raman scattering as detection method. The test strips are prepared on glass fibre paper with silver nanoparticles and a spray method with an airbrush spray setup as a low cost fabrication approach. The properties of the test strips are investigated with three classical Raman analytes rhodamine 6G, 4-aminothiophenol and adenine and optimized for a good reproducibility of the intensity measurements. All test analytes can be identified at low concentrations. For adenine, a concentration series from 10-4 M to 10-8 M is measured and the calibration data can be fitted and evaluated with a Langmuir isotherm model. The optimized test strips are applied for the identification of two antibiotics enoxacin and enrofloxacin.