Rotavirus-associated seizures and reversible corpus callosum lesion

Abstract

Rotavirus is a non-enveloped double-stranded RNA virus that causes severe gastroenteritis in children, but complications are rarely reported. Some reports have shown that rotavirus can in-duce diverse complications of the central nervous system, such as seizures, encephalopathy with a reversible splenial lesion, enceph-alitis, cerebral white matter abnormalities, and cerebellitis. Here, we present a 2-year-old patient with seizures, who had an isolated splenial lesion in the corpus callosum on neuroimaging, and the rotavirus antigen detected in faeces.