Pharmacological Activity of Biosynthesized Gold Nanoparticles from Brown Algae- Seaweed Turbinaria conoides

Abstract

The purpose of in vitro testing in the present study is to demonstrate the anti-diabetic activity and anti-inflammatory activity of biosynthesized gold nanoparticle (AuNp) from Turbinaria conoides. The anti-diabetic activity by different in vitro methods method, anti-inflammatory activity by HRBC membrane stabilization assay and anticoagulant activity by calculating prothrombin time was carried out in the concentration range of (50 µl/ml, 100 µl/ml and 200 µl/ml) respectively. The inhibition rate of gold nanoparticle from Turbinaria conoides exhibited significantly maximum activity of 57.3% at concentration of 200 µg/ml and minimum level inhibition of 42.9% in 50 µl when compared with the standard drug Glinil that showed inhibition of maximum 85.6% and minimum 77.1%.