Aureomycin in ophthalmology

Abstract

(1) Eight cases of resistant conjunctivitis were treated with aureomycin, six successfully. (2) Thirteen cases of follicular conjunctivitis, four with corneal vascularization and ulceration, were treated; ten recovered. (3) Ten of the fourteen cases of long-standing blepharitis treated were clinically cured. Eight of the successes were achieved by local administration only. (4) Six cases of active trachoma received aureomycin; five showed great improvement. (5) Superficial punctate keratitis did not respond to treatment given locally. (6) A case of corneal ulceration and lid ulceration occurring 10 days after vaccination responded dramatically. (7) Local administration of drops produced no benefit in three cases of disciform keratitis. Two cases received subconjunctival injection and one improved rapidly. Sufficient cases have not been so treated to give any conclusive results. (8) Treatment of dendritic ulcers has not been successful. (9) The value of aureomycin in external ophthalmological infections is considerable, particularly in conditions caused by organisms resistant to the older antibiotics and in several types of infection caused, or presumably caused, by viruses. From the general point of view its therapeutic effect in trachoma is probably its most important application; long-term observations with pathological controls will be necessary before its true value in this disease can be properly assessed, but the preliiminary- observations are encouraging.