Molecular mechanisms of bone 18F-NaF deposition

Abstract

There is renewed interest in 18F-NaF bone imaging with PET or PET/CT. The current brief discussion focuses on the molecular mechanisms of 18F-NaF deposition in bone and presents model-based approaches to quantifying bone perfusion and metabolism in the context of preclinical and clinical applications of bone imaging with PET. COPYRIGHT © 2010 by the Society of Nuclear Medicine, Inc.