Revisiting the glyoxylate cycle: Alternate pathways for microbial acetate assimilation

60Citations
Citations of this article
158Readers
Mendeley users who have this article in their library.

This article is free to access.

Abstract

The glyoxylate cycle, identified by Kornberg et al. in 1957, provides a simple and efficient strategy for converting acetyl-CoA into anapleurotic and gluconeogenic compounds. Studies of a number of bacteria capable of growth with C2 compounds as the sole carbon source have revealed that they lack the key glyoxylate cycle enzyme isocitrate lyase, suggesting that alternative pathway(s) for acetate assimilation exist in these bacteria. Recent studies of acetate assimilation in methylotrophs and purple phototrophs have revealed remarkable and complex new pathways for assimilation of acetate in the absence of isocitrate lyase. The details of these new pathways are the subject of this MicroCommentary. © 2006 The Authors.

Cite

CITATION STYLE

APA

Ensign, S. A. (2006, July). Revisiting the glyoxylate cycle: Alternate pathways for microbial acetate assimilation. Molecular Microbiology. https://doi.org/10.1111/j.1365-2958.2006.05247.x

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free