Gangliosides help stabilize the brain

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Abstract

Defects in the breakdown of gangliosides are associated with a class of disorders known as lysosomal storage diseases. Now, a defect in the synthesis of gangliosides, glycolipids that contain sialic acid and are abundant in the brain, has been shown to underlie an inherited form of epilepsy.

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Proia, R. L. (2004, November). Gangliosides help stabilize the brain. Nature Genetics. https://doi.org/10.1038/ng1104-1147

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