Abstract
A solid phase oligonucleotide (ON) synthesis on porous silicon (PSi) chip is presented. The prepared Si-OH surface were analyzed by FT-IR and the OH functions were quantified by reaction with 3'-phosphoramidite nucleotide building block. Short ONs were synthesized on the chip surface and the coupling yields evaluated.
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CITATION STYLE
APA
De Stefano, L., De Tommasi, E., Rea, I., Rotiroti, L., Giangrande, L., Oliviero, G., … Piccialli, G. (2008). Oligonucleotides direct synthesis on porous silicon chip. Nucleic Acids Symposium Series (2004), (52), 721–722. https://doi.org/10.1093/nass/nrn364
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