CP27 localization in the dental lamina basement membrane and in the stellate reticulum of developing teeth

Abstract

cp27 is a novel gene involved in early vertebrate development that features a distinct protein localization pattern in developing tooth organs. During initial tooth development, CP27 was detected at the epithelial-mesenchymal interface of dental lamina stage tooth organs. At later stages of tooth development, CP27 was localized in the stellate reticulum, the oral mucosa mesenchyme, and alveolar bone. The significant changes in the highly restricted distribution pattern suggest that CP27 might be involved at several different levels during tooth development.