Total Synthesis of (±)-Phosphonothrixin, a Novel Herbicidal Antibiotic Containing C-P Bond

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Abstract

Phosphonothrixin (1) is a novel herbicidal agent produced by Saccharothrix sp. ST-888, with a unique structure possessing a C-P bond and an isoprene unit. The total synthesis of this antibiotic was accomplished from methyl (bromomethyl)acrylate in six steps. © 1995, JAPAN ANTIBIOTICS RESEARCH ASSOCIATION. All rights reserved.

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Kimura, T., Kanno, H., & Takahashi, E. (1995). Total Synthesis of (±)-Phosphonothrixin, a Novel Herbicidal Antibiotic Containing C-P Bond. The Journal of Antibiotics, 48(10), 1134–1137. https://doi.org/10.7164/antibiotics.48.1134

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