A clinical and genetic study of Hunter's syndrome. 1. Heterogeneity

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Abstract

Analysis of the natural history in 88 patients with definite or probable Hunter's syndrome indicates that the disease shows both clinical and genetic heterogeneity. Intrafamilial variation was noted in only one of 17 families. Linkage analysis suggests that the Hunter and Xg loci are unlikely to be closely linked.

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Young, I. D., Harper, P. S., Archer, I. M., & Newcombe, R. G. (1982). A clinical and genetic study of Hunter’s syndrome. 1. Heterogeneity. Journal of Medical Genetics, 19(6), 401–407. https://doi.org/10.1136/jmg.19.6.401

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