Inhaled Adjuvants and Eosinophilic Airway Inflammation in Asthma: Is a Little Bit of Lipopolysaccharide the Key to Allergen Sensitization?

Abstract

The compartmentalization of immune responses into innate and adaptive components was a conceptual breakthrough that revolutionized our understanding of immunology. In particular, the idea that activated dendritic cells (DCs) instructed T cell differentiation rapidly gained traction in the 1990s ([1