Validation of respiratory inductive plethysmography (LifeShirt system) (RIPLS) for tidal volume (VT), minute ventilation (VE), and respiratory frequency (fB) was performed among people with untreated obesity hypoventilation syndrome (OHS) and controls. Measures were obtained simultaneously from RIPLS and a spirometer during two tests, and compared using Bland Altman analysis. Among 13 OHS participants (162 paired measures), RIPLS-spirometer agreement was unacceptable for VT: mean difference (MD) 3mL (1%); limits of agreement (LOA) -216 to 220mL (±36%); VE MD 0.1Lmin-1 (2%); LOA -4.1 to 4.3Lmin-1 (±36%); and fB: MD 0.2brmin-1 (2%); LOA -4.6 to 5.0brmin-1 (±27%). Among 13 controls (197 paired measures), RIPLS-spirometer agreement was acceptable for fB: MD -0.1brmin-1 (-1%); LOA -1.2 to 1.1brmin-1 (±12%), but unacceptable for VT: MD 5mL (1%); LOA -160 to 169mL (±20%) and VE: MD 0.1Lmin-1 (1%); LOA -1.4 to 1.5Lmin-1 (±20%). RIPLS produces valid measures of fB among controls but not OHS patients, and is not valid for quantifying respiratory volumes among either group. © 2014 Elsevier B.V.
Hollier, C. A., Harmer, A. R., Maxwell, L. J., Menadue, C., Willson, G. N., Black, D. A., & Piper, A. J. (2014). Validation of respiratory inductive plethysmography (LifeShirt) in obesity hypoventilation syndrome. Respiratory Physiology and Neurobiology, 194(1), 15–22. https://doi.org/10.1016/j.resp.2014.01.014