Analysis of Clinical Efficacy of Glucose and Lipid Metabolism in Children with Growth Hormone Treatment of Turner Syndrome

Abstract

Objective: To investigate the effects of growth hormone on Turner syndrome of glucose and lipid metabolism. Methods: 60 patients in August 2014 - February 2015 between patients with Turner syndrome treatment, all patients using recombinant human growth hormone (rhGH) treatment a year, to observe, record and compare the before and after treatment in patients with triglyceride (TG), total cholesterol (T-CHO), high density lipoprotein (HDL-C), atherogenic index (AI), fasting blood sugar (FBS), serum insulin (FINS), insulin resistance index (IRS), etc. level indicators. Results: After treatment of children AI decreased significantly, other TG, T-CHO, HDL-C, FBS, FINS and other glycolipid metabolism did not change significantly, P> 0.05. Conclusion Turner syndrome growth hormone treatment on lipid metabolism have a certain improvement, no significant effect on carbohydrate metabolism, worthy of clinical application.