Sym004: Truly a new level of anti-EGFR treatment?

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Abstract

Sym004 is a new antibody mixture to target EGFR in metastatic colorectal cancer. Preclinical data suggest efficacy in anti–EGFR-resistant tumors, but it remains unclear whether a higher toxicity is outweighed by those advantages.

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Stintzing, S., & Heinemann, V. (2016). Sym004: Truly a new level of anti-EGFR treatment? Cancer Discovery, 5(6), 578–580. https://doi.org/10.1158/2159-8290.CD-15-0441

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