A review of the efficacy and tolerability of antipsychotic long-acting injections

Abstract

The formulation of long-acting injections (LAIs) as a method of delivering antipsychotics can be used to improve adherence, particularly in those unintentionally non-adherent. Here, the authors review the efficacy and tolerability of first-generation antipsychotic (FGA) and second-generation antipsychotic (SGA) LAIs, analyse drug cost, give guidance on initiation regimens for SGA LAIs and discuss the future for these drugs.