Clinical characteristics and outcomes of COVID-19 in solid organ transplant recipients: A cohort study

Abstract

Solid organ transplant recipients (SOTr) with coronavirus disease 2019 (COVID-19) are expected to have poorer outcomes compared to nontransplant patients because of immunosuppression and comorbidities. The clinical characteristics of 47 SOTr (38 kidneys and 9 nonkidney organs) were compared to 100 consecutive hospitalized nontransplant controls. Twelve of 47 SOTr managed as outpatients were subsequently excluded from the outcome analyses to avoid potential selection bias. Chronic kidney disease (89% vs 57% P =.0007), diabetes (66% vs 33% P =.0007), and hypertension (94% vs 72% P =.006) were more common in the 35 hospitalized SOTr compared to controls. Diarrhea (54% vs 17%, P